1. [PDF] Dosing Chart (Weight in Pounds) - Zoetis
When replacing a monthly heartworm preventive product, ProHeart 12 should be given within one month of the last dose of the former medication to avoid a gap in ...
2. [PDF] Mixing Instructions - Zoetis
ProHeart 6 administered at 3 times the recommended dose in dogs with patent heartworm infections and up to 5 times the recommended dose in ivermectin-sensitive ...
3. ProHeart® 12 (moxidectin)For Extended-Release Injectable ...
The recommended subcutaneous dose is 0.05 mL of the constituted suspension/kg body weight (0.023 mL/lb). This amount of suspension will provide 0.5 mg ...
Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian.
4. ProHeart® 6 (moxidectin)For Extended-Release Injectable ...
Dose. The recommended subcutaneous dose is 0.05 mL of the constituted suspension/kg body weight (0.0227 mL/lb.). This amount of suspension ...
Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian.
5. Proheart SR12 Injection for Dogs - Old Reynella Vet
23 dec 2020 · When administering to puppies they require their first dose at 12-13 weeks of age, then a booster at 6-7 months (usually at the time of desexing) ...
Are you guilty of missing your pets monthly heartworm prevention? With our busy lifestyles, this can be easy to do. The only problem is, heartworm is the one parasite that can cause death in our pets...
6. [PDF] FREEDOM OF INFORMATION SUMMARY - Animal Drugs @ FDA
Conclusion: A single subcutaneous injection of ProHeart 6 given at the recommended dosage of 0.17 mg moxidectin/kg bodyweight was ≥ 90% effective against ...
7. Safety of an extended-release injectable moxidectin suspension ...
6 sep 2019 · The recommended dose is 0.5 mg/kg subcutaneously once yearly. Methods. Study 1: safety margin was evaluated as 3 treatments of PH 12 (0× ( ...
The safety of ProHeart® 12 (PH 12; extended-release injectable suspension; 10% moxidectin in glyceryl tristearate microspheres) was evaluated in four studies using Beagle dogs and one study using ivermectin-sensitive Collies. The recommended dose is 0.5 mg/kg subcutaneously once yearly. Study 1: safety margin was evaluated as 3 treatments of PH 12 (0× (control); 1× (recommended dose); 3× (3 times recommended dose) and 5× (5 times recommended dose) in 12 months via clinical observations, body weights, food consumption, injection site observations, physical examinations, moxidectin tissue assay, pharmaco*kinetics, and clinical and anatomic pathology. Study 2: safety in breeding-age males was demonstrated by sem*n testing at 14-day intervals from Day 7 to Day 91 post-treatment (0× or 3×). Study 3: reproductive safety in females was demonstrated by monitoring dams and litters following treatments (0× or 3×) administered during breeding, gestation, or lactation. Study 4: safety in dogs surgically implanted with adult heartworms was evaluated by clinical and laboratory monitoring following treatment with 0× or 3× administered 61 days post-implantation. Study 5: safety in ivermectin-sensitive dogs (120 µg/kg SC) was by clinical monitoring for 1 week after administering 1×, 3× or 5×. Study 1: slight swelling clinically detectable at some 3× and 5× injection sites was characterized microscopically as granulomatous inflammation, like tissue responses to medical...
8. ProHeart 12 for Pet Owners | Zoetis Petcare
Just one dose of ProHeart 12 provides protection for your dog all year long. It can be tough to remember monthly medications for your dog, and heartworm ...
Just one dose of ProHeart 12 provides protection for your dog all year long. Ask your vet about the ONE.
9. Heartworm Treatment Dosage Calculator
Along with the dosage calculator and detailed, step-by-step display of ... chart and video for use when explaining how heartworms infect a pet.
We have developed a web-based app to benefit veterinary professionals. Now treating dogs with heartworm disease is more straightforward than ever....
10. ProHeart 6 - Zoetis Inc.: Veterinary Package Insert - Vet Label
23 mrt 2022 · The recommended subcutaneous dose is 0.05 mL of the constituted suspension/kg body weight (0.0227 mL/lb.). This amount of suspension will ...
Zoetis Inc.: ProHeart 6 (moxidectin) for extended-release injectable suspension consists of two separate vials: One vial contains 10% moxidectin sterile microspheres and the second vial contains a...
11. Moxidectin (ProHeart®, Cydectin®, Advantage® Multi) for Dogs and Cats
11 aug 2015 · Dosing Information of Moxidectin for Dogs and Cats · Medication should never be administered without first consulting your veterinarian. · In dogs ...
Moxidectin (ProHeart®, Cydectin®, Advantage® Multi) for Dogs and Cats
12. ProHeart® 12, a moxidectin extended-release injectable ...
26 jul 2019 · All of the HG Plus product was supplied by the veterinary clinic based on the most recent body weight of the dog and the dosage chart for HG ...
The efficacy of an extended-release injectable moxidectin (0.5 mg/kg) suspension (ProHeart® 12) (PH 12) in preventing the development of Dirofilaria immitis in dogs for 12 months was investigated in laboratory and field studies in the USA. In each of two laboratory studies, 20 dogs ≥ 12 months of age were randomly allocated to receive a subcutaneous injection of saline or PH 12 on Day 0 and were then inoculated with 50 D. immitis third-stage larvae (L3) on Day 365. All dogs were necropsied ~ 5 months post-inoculation for adult worm counts. The field efficacy study included dogs ≥ 10 months of age from 19 veterinary clinics in the USA treated with either 20 monthly doses of Heartgard® Plus (HG Plus) (296 dogs) or two doses of PH 12 (297 dogs) on Days 0 and 365. Efficacy was determined on Days 365, 480 and 605 using adult HW antigen and microfilaria testing to assess adult HW infection. PH 12 was 100% effective in preventing HW disease in all three of these studies. In the laboratory studies, no PH 12-treated dogs had any adult HWs, whereas all control dogs in both studies had adult HWs [geometric mean, 30.2 (range, 22–37) for Study 1 and 32.6 (22–44) for Study 2]. In the field study, all dogs treated with PH 12 tested negative for adult HW infection on all test days (Days, 365, 480 and 605), whereas four dogs receiving HG Plus (positive control) tested positive for HWs during the study (three dogs on Day 365 and one dog on Day 480). All four dogs treated with HG Plus...
13. Proheart Injection For Dogs | Southern Cross Vet Clinic
14 mrt 2018 · Why we're Pro-Proheart · What are heartworms and how do they cause disease? · Do I need to protect my pets against heartworm? · Why monthly dosing ...
If you reliy on monthly tablets for preventing heartworm, your dog likely isn’t actually protected against heartworm right now.
14. Heartworm Preventive Comparison Chart for Dogs and Cats
Proheart 6, Proheart 12. every 6 months for Proheart 6, every 12 months for Proheart 12. yes. yes. No, in fact, owner must agree to pre-treatment labwork ...
Confused about heartworm protection? This chart compares the popular heartworm preventives to assist you in determining which is right for your situation.
